ncRNA name | hsa-miR-34a |
ncRNA Category | miRNA |
Disease name | cataract |
Species | Homo sapiens |
Tissues/Cell_line | lens capsule samples; human lens epithelial cell line SRA01/04; human embryonic kidney cell line HEK293T |
Methods | qRT-PCR, luciferase reporter assay, flow cytometry, CCK-8 assay, TUNEL, immunofluorescence, Western blot |
Expression pattern | associated |
Functional description | miR-34a suppressed the proliferation and induced apoptosis of SRA01/04 cells by downregulating E2F3. |
PubMed ID | 27840975 |
Year | 2016 |
Title | miR‑34a suppresses proliferation and induces apoptosis of human lens epithelial cells by targeting E2F3. |
Drug-related ncRNA | NO |
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