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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of cataract
ncRNA name hsa-miR-34a
ncRNA Category miRNA
Disease name cataract
Species Homo sapiens
Tissues/Cell_line lens capsule samples; human lens epithelial cell line SRA01/04; human embryonic kidney cell line HEK293T
Methods qRT-PCR, luciferase reporter assay, flow cytometry, CCK-8 assay, TUNEL, immunofluorescence, Western blot
Expression pattern associated
Functional description miR-34a suppressed the proliferation and induced apoptosis of SRA01/04 cells by downregulating E2F3.
PubMed ID 27840975
Year 2016
Title miR‑34a suppresses proliferation and induces apoptosis of human lens epithelial cells by targeting E2F3.
Drug-related ncRNA NO

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